Back to Basics!

The next 2-3 weeks I will be writing about DHEA and Pregnenolone, two hormones of more importance than many people know.

First, there is a cascade of how hormones are made. It starts with cholesterol!  Not only is cholesterol not a bad guy, it is one of the most vitally important substances in your body.

Cholesterol is the precursor of all steroid hormones and many doctors are on a mission to get rid of cholesterol.  Why?

Steroid Hormone Cascade

  • Cholesterol converts to Pregnenolone.
  • Pregnenolone converts to 1 of 3 different hormones.
  • DHEA,
  • Progesterone,
  • Cortisol
  • DHEA converts to Testosterone
  • Testosterone converts to Estrogen
  • Progesterone converts to Aldosterone
  • Cortisol is an end hormone as it does not convert into another hormone.

Pregnenolone is nicknamed ” the mother hormone”.  It is a precursor hormone to all other steroid hormones.   Made in the brain it is referred to as a neurosteroid.  It is mostly made in the adrenal glands, followed by the ovaries and testes.

What Does Pregnenolone Do In the Body?   Why is it important?

  • It is the most potent memory enhancer in our bodies.
  • It is the most important hormone in maintaining cognitive functioning.
  • Promotes logical thinking
  • It reduces the risk of dementia.
  • It alleviates anxiety.
  • It alleviates depression.
  • It is a potent anti-inflammatory.
  • It can improve mental health disorders
  • Low levels can be used as a premature marker for Alzheimers.
  • Improves energy mentally and physically
  • Protects the brain!
  • Helps reverse PTSD in Traumatic Brain Injury patients
  • Helps you sleep at night

Before Prednisone was developed, Pregnenolone was used as an anti-inflammatory for asthma, chrons disease, rheumatoid arthritis and other inflammatory diseases.

I will guarantee, you now know 100% more than your physicians!Ask your MD what pregnenolone is and what it does sometime. I would be interested in hearing what they say.

Have an awesome day!  And take your pregnenolone if your levels are low or low normal!

Dr. D

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